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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1E All Species: 13.03
Human Site: T1385 Identified Species: 28.67
UniProt: Q15878 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15878 NP_000712.2 2313 261731 T1385 L Q H S V D V T E E D R G P S
Chimpanzee Pan troglodytes XP_520396 2784 310342 T1826 L K H S V D A T Y E E Q G P S
Rhesus Macaque Macaca mulatta XP_001110352 2383 269535 T1382 L Q H S V D V T E E D R G P S
Dog Lupus familis XP_547425 2465 277756 T1527 L Q H S V D V T E E D R G P S
Cat Felis silvestris
Mouse Mus musculus Q61290 2272 257217 W1377 T V S T G E G W P Q V L Q H S
Rat Rattus norvegicus Q07652 2222 252098 W1326 T V S T G E G W P Q V L Q H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 M1258 S K L F N D A M D I M N M V F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XVR3 1829 207718 P943 P P E P E P E P E E V E E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91645 1851 212452 W965 P K Q E L R V W K P R A F H Y
Honey Bee Apis mellifera NP_001159376 1904 215872 L1018 T I K R V P K L K A V F D C V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186699 1966 222605 F1079 E Q G D Q D F F D G E I D K N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.8 95.8 90.7 N.A. 94.6 92.5 N.A. N.A. 26.4 N.A. 20.4 N.A. 43.5 46.2 N.A. 39.5
Protein Similarity: 100 57.8 96.3 92 N.A. 95.8 93.8 N.A. N.A. 41.9 N.A. 37.4 N.A. 55.8 57.8 N.A. 52.5
P-Site Identity: 100 66.6 100 100 N.A. 6.6 6.6 N.A. N.A. 6.6 N.A. 13.3 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 86.6 100 100 N.A. 26.6 26.6 N.A. N.A. 20 N.A. 13.3 N.A. 26.6 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 0 0 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 10 0 55 0 0 19 0 28 0 19 0 0 % D
% Glu: 10 0 10 10 10 19 10 0 37 46 19 10 10 10 10 % E
% Phe: 0 0 0 10 0 0 10 10 0 0 0 10 10 0 10 % F
% Gly: 0 0 10 0 19 0 19 0 0 10 0 0 37 0 0 % G
% His: 0 0 37 0 0 0 0 0 0 0 0 0 0 28 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 28 10 0 0 0 10 0 19 0 0 0 0 10 0 % K
% Leu: 37 0 10 0 10 0 0 10 0 0 0 19 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 10 0 10 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 19 10 0 10 0 19 0 10 19 10 0 0 0 37 0 % P
% Gln: 0 37 10 0 10 0 0 0 0 19 0 10 19 0 0 % Q
% Arg: 0 0 0 10 0 10 0 0 0 0 10 28 0 0 0 % R
% Ser: 10 0 19 37 0 0 0 0 0 0 0 0 0 0 55 % S
% Thr: 28 0 0 19 0 0 0 37 0 0 0 0 0 0 0 % T
% Val: 0 19 0 0 46 0 37 0 0 0 37 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _